Biological properties of different extracts derived from body wall and cuvierian tubules of pearsonothuria graeffei semper (Black-spotted Sea Cucumber)
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2016-12
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Don Mariano Marcos Memorial State University - South La Union Campus
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In this study, unadulterated doses of crude BWME (MIC, <218.75 ug/ml against Staphylococcus aureus ATCC 25923) and BWEAE (MIC, <218.75 pg/mi against S. aureus ATCC 25923; MIC, <437.50 pg/ml against Escherichia coli ATCC 25922) both showed weak antibacterial property compared to Ciprofloxacin (5 ug/ml). However, a dose of crude BWME (MIC, 1750 pg/ml) and BWHE (MIC, 1750 ug/ml) exhibited a significant (p < 0.05) antifungal property against Candida albicans ATCC 10231 compared to Clotrimazole (10 ug/ml ), Fluconazole (25 pg/ml), and Ketoconazole (10 Hg/m).
Pearsonothuria graeffei crude extracts are potential cytotoxic and genotoxic agents at concentrations of 500, 1000, and 1500 pg/ml. Also, a significant (p < 0.03) growth inhibition in both the length and number of roots occurred at higher concentrations of 1000 and 1500 pg/ml of the crude extracts. Finally, a low mitotic index was observed in onions treated with the crude extracts.
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Torres, J.R.D. (2016). Biological properties of different extracts derived from body wall and cuvierian tubules of pearsonothuria graeffei semper (Black-spotted Sea Cucumber). [Unpublished Master's Thesis]. Don Mariano Marcos Memorial State University - South La Union Campus, Agoo, La Union. Lakasa ti Sirib, DMMMSU Institutional Repository.
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