Browsing by Author "Pelotin, Alejandro S., II"

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    Development and field trial of autogenous escherichia coli vaccine against piglet scour
    (Don Mariano Marcos Memorial State University - North La Union Campus, 2008-03) Pelotin, Alejandro S., II
    This study was conducted with the following objectives: (a) to develop an effective autogenous E. coli vaccine against piglet scour; (b) to determine the most effective dose of autogenous E. coli vaccine against piglet scour; (c) to determine the performance of piglets passively vaccinated with autogenous E. coli vaccine against piglet scour; and (d) to determine the economic feasibility of using autogenous E. coli vaccine against piglet scour. A total of twenty four gestating sows regardless of breed and number of parity and their subsequent litter were used in the study. They were distributed into four treatments and replicated three times with two sows per replicate following Complete Randomized Design (CRD). The treatments were as follows: To - control (without vaccine); T[ - 107 bacterial cell/dose; T2 - 108 bacterial cell/dose; and T3 - 109 bacterial cell/dose. Escherichia coli was isolated, purified and mass cultivated. It was processed into autogenous vaccine. The vaccine was subjected to sterility and safety tests before administration to gestating sows a month prior to farrrowing. After farrowing, the litter of each sow was observed for the occurrence of diarrhea. Data gathered were analyzed using Analysis of Variance (ANOVA) and Least Significant Difference (LSD). Results revealed that autogenous E. coli vaccine can effectively control piglet scour. A concentration of 107 bacterial cell/dose can be used to passively vaccinate piglets against piglet scour. Passive vaccination with autogenous E. coli vaccine affects the performance of piglets. Autogenous E. coli vaccine is cost-effective in the prevention of piglet scour.